mRNA vaccines sometimes led to nonsense proteins being made instead of the desired Covid “spike”
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More than a quarter of people injected with mRNA Covid jabs suffered an unintended immune response created by a glitch in the way the vaccine was read by the body, a study has found.
No adverse effects were created by the error, data show, but Cambridge scientists found such vaccines were not perfect and sometimes led to nonsense proteins being made instead of the desired Covid “spike”, which mimics infection and leads to antibody production
sourceThe study itself is this one...
N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting - NatureA study demonstrates that nucleotide modifications in mRNA-based therapeutics can lead to +1 ribosomal frameshifting during translation, yielding products that can trigger immune responses.
N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting - NatureA study demonstrates that nucleotide modifications in mRNA-based therapeutics can lead to +1 ribosomal frameshifting during translation, yielding products that can trigger immune responses.